No particular dose adjustment encouraged when tofacitinib coadministered with strong CYP2C19 inhibitors; reduce tofacitinib dose if coadministered with the two reasonable CYP3A4 and strong CYP2C19 inhibitors .Allergic reactions like rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome might hardly ever be brought on by an immunological res

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